Hi,
It depends on how huge your map will be and also how you design it.
Providing you use spritesheets then your texture memory will not increase regardless of map size.
If your images are small e.g. 16x16 then you could encounter system memory problems due to the number you need to add to populate a level and would probably be better to use a tile based system with culling.
Although LD does not currently support culling it does have other tricks like the ability to wrap/repeat layers and the layers can be different sizes.
So as you scroll the background and clouds for example they could wrap over 2 screens whereas the foreground layer could be over 20 screens.
Also with LD because it does not rely on uniform tiles, the background could be 1 object and the clouds 2 objects whereas in a tile based system they would be probably be made up from many display objects pieced together.
There are pros and cons to both so it does depend on the type of game.